TY - JOUR AU - Atici, Tu?ba AU - Altun Çolak, Deniz PY - 2021/04/16 Y2 - 2024/03/29 TI - The role of oleuropein against nanocomposite toxicity in fruit fly: evidence for lifespan extension JF - Caryologia JA - Caryologia VL - 73 IS - 3 SE - Articles DO - 10.13128/caryologia-226 UR - https://riviste.fupress.net/index.php/caryologia/article/view/226 SP - AB - <p class="p1">The effect of zinc oxide/titanium dioxide nanocomposite the lifespan of the fruit fly <span class="s1">Drosophila melanogaster</span> and the protective role of oleuropein, a strong antioxidant, against the zinc oxide/titanium dioxide were investigated. Chemicals prepared in different concentrations (0.005, 0.1, 0.5, and 1 g/L for zinc oxide/titanium dioxide; 0.1 mmol/L for oleuropein) have been separately applied to female and male populations of<span class="s1"> D. melanogaster</span> for the control and application groups. In both female and male populations, it has been observed that zinc oxide/titanium dioxide has decreased the lifespan and oleuropein has increased the lifespan according to the control group, depending on the concentration. These findings demonstrate the beneficial effect of oleuropein, suggested as a protective role in the prevention of zinc oxide/titanium dioxide induced developmental toxicity.</p> ER -